CXCR4-modification enhances CAR-T efficacy by improving tumor tracking and bone marrow homing in B-cell malignancies

CXCR4-modification enhances CAR-T efficacy by improving tumor tracking and bone marrow homing in B-cell malignancies

Lentivirus-mediated gene transduction downregulates CXCR4 expression on the T cell surface To investigate the potential influence…

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Genetic modification enhances “living drugs” for blood cancers

Genetic modification enhances “living drugs” for blood cancers

CAR T cells are patient-derived, genetically engineered immune cells. They are “living drugs” and constitute a…

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New gene modification enhances CAR-T cell effectiveness against cancer

New gene modification enhances CAR-T cell effectiveness against cancer

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found…

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